میزان تأثیر سه روش تمرینی وامانده ساز هوازی، بی‌هوازی و مقاومتی بر سیستم اندوکانابینوئید در مردان جوان: یک کارآزمایی بالینی

Background and Objectives: One of the most common challenges for human physiological system is exercise. Therefore, the aim of this study was determining the effect of different types of exercise on endocannabinoid system agents such as anandamide (AEA) and 2-arsidonyl glycerol (2-AG). Materials and Methods: In this clinical trial study, 32 young men (19-25 years old) volunteered from among students of Islamic Azad University of Babol, who did not have any regular sports activities. They were randomly divided into four groups of eight persons. After having the same breakfast, the subjects’ blood were taken before and after short time aerobic exercise (running training with oxigen consumption of 70% of maximal heart rate until full exhaustion), anaerobic exercise (running training with maximum intensity until full exhaustion) and resistance exercise (with 8 stations until full exhaustion). The control group did not do any exercise. The anandamide and 2-arsidonyl glycerol factors were evaluated by ELISA method. Data were analyzed using ANOVA, ANCOVA and paired t-test method. Results: The results of this study showed that short time aerobic, anaerobic and resistance exercise did not have any significant effect on endocannabinoid system factors (p> 0.05). Conclusion: The results of this study showed that endocannabinoid system is not affected by different training methods until exhaustion. Key words: Endocannabinoid system, Anandamide, 2-arsidonyl glycerol, Aerobic exercise, Anaerobic exercise, Resistance exercise.   Funding: This research was funded by Hakim Sabzevari University. Conflict of interes: None declared. Ethical approval: The Ethics Committee of Sabzevar University of Medical Sciences approved the study (MEDSAB.REC.1395.127)     How to cite this article: Sharifi M, Hamedinia MR, Hosseini-Kakhak SA. Investigating the Effect of Three Methods of Aerobic, Anaerobic and Resistance Exhaustive Exercise on Endocannabinoid System in Young Men: A Clinical Trial. J Rafsanjan Univ Med Sci 2018; 17 (9): 855-64. [Farsi]